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Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells

Type 1 cannabinoid receptors (CB1Rs) are widely expressed in the vertebrate retina, but the role of endocannabinoids in vision is not fully understood. Here, we identified a novel mechanism underlying a CB1R-mediated increase in retinal ganglion cell (RGC) intrinsic excitability acting through AMPK-...

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Detalles Bibliográficos
Autores principales: Miraucourt, Loïs S, Tsui, Jennifer, Gobert, Delphine, Desjardins, Jean-François, Schohl, Anne, Sild, Mari, Spratt, Perry, Castonguay, Annie, De Koninck, Yves, Marsh-Armstrong, Nicholas, Wiseman, Paul W, Ruthazer, Edward S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987138/
https://www.ncbi.nlm.nih.gov/pubmed/27501334
http://dx.doi.org/10.7554/eLife.15932

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