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VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking

Ras guanosine triphosphatases (GTPases) regulate signaling pathways only when associated with cellular membranes through their C-terminal prenylated regions. Ras proteins move between membrane compartments in part via diffusion-limited, fluid phase transfer through the cytosol, suggesting that chape...

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Detalles Bibliográficos
Autores principales:	Zhou, Mo, Wiener, Heidi, Su, Wenjuan, Zhou, Yong, Liot, Caroline, Ahearn, Ian, Hancock, John F., Philips, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987297/ https://www.ncbi.nlm.nih.gov/pubmed/27502489 http://dx.doi.org/10.1083/jcb.201604061

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