Intra-Articular Pigmentation of Synovium: An Unusual Cause

An unusual grayish brown discoloration of the synovium was found during a knee arthroscopy of a 72-year-old man. He also had similar pigmentation affecting the skin on the legs, arms, hands, and face. It was found he had been taking 400 mg of amiodarone hydrochloride daily for last 7 years. Amiodaro...

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Detalles Bibliográficos
Autores principales: Verma, Shobhit, Hamilton, Steven, Liew, Sue M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Orthopaedic Association 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987319/
https://www.ncbi.nlm.nih.gov/pubmed/27583118
http://dx.doi.org/10.4055/cios.2016.8.3.330
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author Verma, Shobhit
Hamilton, Steven
Liew, Sue M
author_facet Verma, Shobhit
Hamilton, Steven
Liew, Sue M
author_sort Verma, Shobhit
collection PubMed
description An unusual grayish brown discoloration of the synovium was found during a knee arthroscopy of a 72-year-old man. He also had similar pigmentation affecting the skin on the legs, arms, hands, and face. It was found he had been taking 400 mg of amiodarone hydrochloride daily for last 7 years. Amiodarone is known to cause a slate grey pigmentation of skin and cornea, but we believe this is the first report of amiodarone-induced pigmentation of the synovium. The arthroscopist should be aware of the possibility of drug-related synovial pigmentation and include this in differential diagnosis.
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spelling pubmed-49873192016-09-01 Intra-Articular Pigmentation of Synovium: An Unusual Cause Verma, Shobhit Hamilton, Steven Liew, Sue M Clin Orthop Surg Case Report An unusual grayish brown discoloration of the synovium was found during a knee arthroscopy of a 72-year-old man. He also had similar pigmentation affecting the skin on the legs, arms, hands, and face. It was found he had been taking 400 mg of amiodarone hydrochloride daily for last 7 years. Amiodarone is known to cause a slate grey pigmentation of skin and cornea, but we believe this is the first report of amiodarone-induced pigmentation of the synovium. The arthroscopist should be aware of the possibility of drug-related synovial pigmentation and include this in differential diagnosis. The Korean Orthopaedic Association 2016-09 2016-08-10 /pmc/articles/PMC4987319/ /pubmed/27583118 http://dx.doi.org/10.4055/cios.2016.8.3.330 Text en Copyright © 2016 by The Korean Orthopaedic Association http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Verma, Shobhit
Hamilton, Steven
Liew, Sue M
Intra-Articular Pigmentation of Synovium: An Unusual Cause
title Intra-Articular Pigmentation of Synovium: An Unusual Cause
title_full Intra-Articular Pigmentation of Synovium: An Unusual Cause
title_fullStr Intra-Articular Pigmentation of Synovium: An Unusual Cause
title_full_unstemmed Intra-Articular Pigmentation of Synovium: An Unusual Cause
title_short Intra-Articular Pigmentation of Synovium: An Unusual Cause
title_sort intra-articular pigmentation of synovium: an unusual cause
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987319/
https://www.ncbi.nlm.nih.gov/pubmed/27583118
http://dx.doi.org/10.4055/cios.2016.8.3.330
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