MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis

DNA double strand break (DSB) repair is critical for generation of B-cell receptors, which are pre-requisite for B-cell progenitor survival. However, the transcription factors that promote DSB repair in B cells are not known. Here we show that MEF2C enhances the expression of DNA repair and recombin...

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Detalles Bibliográficos
Autores principales: Wang, Wenyuan, Org, Tonis, Montel-Hagen, Amélie, Pioli, Peter D., Duan, Dan, Israely, Edo, Malkin, Daniel, Su, Trent, Flach, Johanna, Kurdistani, Siavash K., Schiestl, Robert H., Mikkola, Hanna K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987520/
https://www.ncbi.nlm.nih.gov/pubmed/27507714
http://dx.doi.org/10.1038/ncomms12376

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