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Imipenem represses CRISPR-Cas interference of DNA acquisition through H-NS stimulation in Klebsiella pneumoniae

Analysis of the genome of Klebsiella pneumoniae NTUH-K2044 strain revealed the presence of two clustered regularly interspaced short palindromic repeats (CRISPR) arrays separated with CRISPR-associated (cas) genes. Carbapenem-resistant K. pneumoniae isolates were observed to be less likely to have C...

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Detalles Bibliográficos
Autores principales: Lin, Tzu-Lung, Pan, Yi-Jiun, Hsieh, Pei-Fang, Hsu, Chun-Ru, Wu, Meng-Chuan, Wang, Jin-Town
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987720/
https://www.ncbi.nlm.nih.gov/pubmed/27531594
http://dx.doi.org/10.1038/srep31644