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PepComposer: computational design of peptides binding to a given protein surface

There is a wide interest in designing peptides able to bind to a specific region of a protein with the aim of interfering with a known interaction or as starting point for the design of inhibitors. Here we describe PepComposer, a new pipeline for the computational design of peptides binding to a giv...

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Detalles Bibliográficos
Autores principales: Obarska-Kosinska, Agnieszka, Iacoangeli, Alfredo, Lepore, Rosalba, Tramontano, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987918/
https://www.ncbi.nlm.nih.gov/pubmed/27131789
http://dx.doi.org/10.1093/nar/gkw366