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Peptiderive server: derive peptide inhibitors from protein–protein interactions

The Rosetta Peptiderive protocol identifies, in a given structure of a protein–protein interaction, the linear polypeptide segment suggested to contribute most to binding energy. Interactions that feature a ‘hot segment’, a linear peptide with significant binding energy compared to that of the compl...

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Detalles Bibliográficos
Autores principales: Sedan, Yuval, Marcu, Orly, Lyskov, Sergey, Schueler-Furman, Ora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987930/
https://www.ncbi.nlm.nih.gov/pubmed/27141963
http://dx.doi.org/10.1093/nar/gkw385