Cargando…

HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering

HotSpot Wizard 2.0 is a web server for automated identification of hot spots and design of smart libraries for engineering proteins’ stability, catalytic activity, substrate specificity and enantioselectivity. The server integrates sequence, structural and evolutionary information obtained from 3 da...

Descripción completa

Detalles Bibliográficos
Autores principales: Bendl, Jaroslav, Stourac, Jan, Sebestova, Eva, Vavra, Ondrej, Musil, Milos, Brezovsky, Jan, Damborsky, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987947/
https://www.ncbi.nlm.nih.gov/pubmed/27174934
http://dx.doi.org/10.1093/nar/gkw416