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HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering
HotSpot Wizard 2.0 is a web server for automated identification of hot spots and design of smart libraries for engineering proteins’ stability, catalytic activity, substrate specificity and enantioselectivity. The server integrates sequence, structural and evolutionary information obtained from 3 da...
Autores principales: | Bendl, Jaroslav, Stourac, Jan, Sebestova, Eva, Vavra, Ondrej, Musil, Milos, Brezovsky, Jan, Damborsky, Jiri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987947/ https://www.ncbi.nlm.nih.gov/pubmed/27174934 http://dx.doi.org/10.1093/nar/gkw416 |
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