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miRNAFold: a web server for fast miRNA precursor prediction in genomes
Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In par...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987958/ https://www.ncbi.nlm.nih.gov/pubmed/27242364 http://dx.doi.org/10.1093/nar/gkw459 |
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author | Tav, Christophe Tempel, Sébastien Poligny, Laurent Tahi, Fariza |
author_facet | Tav, Christophe Tempel, Sébastien Poligny, Laurent Tahi, Fariza |
author_sort | Tav, Christophe |
collection | PubMed |
description | Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In particular, ab initio methods are usually required when predicting novel miRNAs. Here we present a web server dedicated for miRNA precursors identification at a large scale in genomes. It is based on an algorithm called miRNAFold that allows predicting miRNA hairpin structures quickly with high sensitivity. miRNAFold is implemented as a web server with an intuitive and user-friendly interface, as well as a standalone version. The web server is freely available at: http://EvryRNA.ibisc.univ-evry.fr/miRNAFold. |
format | Online Article Text |
id | pubmed-4987958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-49879582016-08-22 miRNAFold: a web server for fast miRNA precursor prediction in genomes Tav, Christophe Tempel, Sébastien Poligny, Laurent Tahi, Fariza Nucleic Acids Res Web Server issue Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In particular, ab initio methods are usually required when predicting novel miRNAs. Here we present a web server dedicated for miRNA precursors identification at a large scale in genomes. It is based on an algorithm called miRNAFold that allows predicting miRNA hairpin structures quickly with high sensitivity. miRNAFold is implemented as a web server with an intuitive and user-friendly interface, as well as a standalone version. The web server is freely available at: http://EvryRNA.ibisc.univ-evry.fr/miRNAFold. Oxford University Press 2016-07-08 2016-05-29 /pmc/articles/PMC4987958/ /pubmed/27242364 http://dx.doi.org/10.1093/nar/gkw459 Text en © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Web Server issue Tav, Christophe Tempel, Sébastien Poligny, Laurent Tahi, Fariza miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title | miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title_full | miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title_fullStr | miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title_full_unstemmed | miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title_short | miRNAFold: a web server for fast miRNA precursor prediction in genomes |
title_sort | mirnafold: a web server for fast mirna precursor prediction in genomes |
topic | Web Server issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987958/ https://www.ncbi.nlm.nih.gov/pubmed/27242364 http://dx.doi.org/10.1093/nar/gkw459 |
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