HABP2 germline variants are uncommon in familial nonmedullary thyroid cancer

BACKGROUND: The genetic basis of nonsyndromic familial nonmedullary thyroid cancer (FNMTC) is poorly understood. A recent study identified HABP2 as a tumor suppressor gene and identified a germline variant (G534E) in an extended FNMTC kindred. The relevance of this to other FNMTC kindreds is uncerta...

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Detalles Bibliográficos
Autores principales: Weeks, Alexia L., Wilson, Scott G., Ward, Lynley, Goldblatt, Jack, Hui, Jennie, Walsh, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988026/
https://www.ncbi.nlm.nih.gov/pubmed/27530615
http://dx.doi.org/10.1186/s12881-016-0323-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988026/
https://www.ncbi.nlm.nih.gov/pubmed/27530615
http://dx.doi.org/10.1186/s12881-016-0323-1

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