LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea

In the developing cochlea, Wnt/β-catenin signaling positively regulates the proliferation of precursors and promotes the formation of hair cells by up-regulating Atoh1 expression. Not much, however, is known about the regulation of Wnt/β-catenin activity in the cochlea. In multiple tissues, the acti...

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Detalles Bibliográficos
Autores principales: Żak, Magdalena, van Oort, Thijs, Hendriksen, Ferry G., Garcia, Marie-Isabelle, Vassart, Gilbert, Grolman, Wilko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988241/
https://www.ncbi.nlm.nih.gov/pubmed/27559308
http://dx.doi.org/10.3389/fncel.2016.00186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988241/
https://www.ncbi.nlm.nih.gov/pubmed/27559308
http://dx.doi.org/10.3389/fncel.2016.00186

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