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Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients

OBJECTIVE: Signaling pathways such as extracellular regulated kinase/mitogen activated protein kinase (ERK/MAPK) have increased activity in leukemia. Ribosomal 6 kinase (RSK4) is a factor downstream of the MAPK/ERK pathway and an important tumor suppressor which inhibits ERK trafficking. Decrease in...

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Detalles Bibliográficos
Autores principales:	Rafiee, Mohammad, Keramati, Mohammad Reza, Ayatollahi, Hosein, Sadeghian, Mohammad Hadi, Barzegar, Mohieddin, Asgharzadeh, Ali, Alinejad, Mohsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988414/ https://www.ncbi.nlm.nih.gov/pubmed/27540520

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