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Similar molecular determinants on Rem mediate two distinct modes of inhibition of Ca(V)1.2 channels
Rad/Rem/Rem2/Gem (RGK) proteins are Ras-like GTPases that potently inhibit all high-voltage-gated calcium (Ca(V)1/Ca(V)2) channels and are, thus, well-positioned to tune diverse physiological processes. Understanding how RGK proteins inhibit Ca(V) channels is important for perspectives on their (pat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988437/ https://www.ncbi.nlm.nih.gov/pubmed/27115600 http://dx.doi.org/10.1080/19336950.2016.1180489 |