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Similar molecular determinants on Rem mediate two distinct modes of inhibition of Ca(V)1.2 channels

Rad/Rem/Rem2/Gem (RGK) proteins are Ras-like GTPases that potently inhibit all high-voltage-gated calcium (Ca(V)1/Ca(V)2) channels and are, thus, well-positioned to tune diverse physiological processes. Understanding how RGK proteins inhibit Ca(V) channels is important for perspectives on their (pat...

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Detalles Bibliográficos
Autores principales: Puckerin, Akil A., Chang, Donald D., Subramanyam, Prakash, Colecraft, Henry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988437/
https://www.ncbi.nlm.nih.gov/pubmed/27115600
http://dx.doi.org/10.1080/19336950.2016.1180489

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