Evaluation of Three Amorphous Drug Delivery Technologies to Improve the Oral Absorption of Flubendazole

This study investigates 3 amorphous technologies to improve the dissolution rate and oral bioavailability of flubendazole (FLU). The selected approaches are (1) a standard spray-dried dispersion with hydroxypropylmethylcellulose (HPMC) E5 or polyvinylpyrrolidone-vinyl acetate 64, both with Vitamin E...

Descripción completa

Detalles Bibliográficos
Autores principales: Vialpando, Monica, Smulders, Stefanie, Bone, Scott, Jager, Casey, Vodak, David, Van Speybroeck, Michiel, Verheyen, Loes, Backx, Katrien, Boeykens, Peter, Brewster, Marcus E., Ceulemans, Jens, Novoa de Armas, Hector, Van Geel, Katrien, Kesselaers, Emma, Hillewaert, Vera, Lachau-Durand, Sophie, Meurs, Greet, Psathas, Petros, Van Hove, Ben, Verreck, Geert, Voets, Marieke, Weuts, Ilse, Mackie, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988473/
https://www.ncbi.nlm.nih.gov/pubmed/27113473
http://dx.doi.org/10.1016/j.xphs.2016.03.003

Ejemplares similares

Ejemplares similares