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Immunotoxin Against a Donor MHC Class II Molecule Induces Indefinite Survival of Murine Kidney Allografts

Rejection of donor organs depends on the trafficking of donor passenger leukocytes to the secondary lymphoid organs of the recipient to elicit an immune response via the direct antigen presentation pathway. Therefore, the depletion of passenger leukocytes may be clinically applicable as a strategy t...

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Detalles Bibliográficos
Autores principales: Brown, K., Nowocin, A. K., Meader, L., Edwards, L. A., Smith, R. A., Wong, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988511/
https://www.ncbi.nlm.nih.gov/pubmed/26799449
http://dx.doi.org/10.1111/ajt.13584