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Super pharmacological levels of calcitriol (1,25-(OH)(2)D(3)) inhibits mineral deposition and decreases cell proliferation in a strain dependent manner in chicken mesenchymal stem cells undergoing osteogenic differentiation in vitro

The biologically active form of vitamin D(3), calcitriol (1,25-(OH)(2)D(3)), plays a key role in mineral homeostasis and bone formation and dietary vitamin D(3) deficiency is a major cause of bone disorders in poultry. Supplementary dietary cholecalciferol (25-hydroxyvitamin D, 25-OH), the precursor...

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Detalles Bibliográficos
Autores principales: Pande, Vivek V., Chousalkar, Kapil C., Bhanugopan, Marie S., Quinn, Jane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Poultry Science Association, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988625/
https://www.ncbi.nlm.nih.gov/pubmed/26500277
http://dx.doi.org/10.3382/ps/pev284

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