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Polymyxin B Nephrotoxicity: From Organ to Cell Damage
Polymyxins have a long history of dose-limiting toxicity, but the underlying mechanism of polymyxin B-induced nephrotoxicity is unclear. This study investigated the link between the nephrotoxic effects of polymyxin B on renal metabolic functions and mitochondrial morphology in rats and on the struct...
Autores principales: | Vattimo, Maria de Fátima Fernandes, Watanabe, Mirian, da Fonseca, Cassiane Dezoti, Neiva, Luciana Barros de Moura, Pessoa, Edson Andrade, Borges, Fernanda Teixeira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988638/ https://www.ncbi.nlm.nih.gov/pubmed/27532263 http://dx.doi.org/10.1371/journal.pone.0161057 |
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