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Therapy-Emergent Drug Resistance to Integrase Strand Transfer Inhibitors in HIV-1 Patients: A Subgroup Meta-Analysis of Clinical Trials

BACKGROUND: Integrase strand transfer inhibitors (INSTIs) are a novel class of anti-HIV agents that show high activity in inhibiting HIV-1 replication. Currently, licensed INSTIs include raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG); these drugs have played a critical role in AIDS the...

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Detalles Bibliográficos
Autores principales:	You, Jiangzhou, Wang, Hongren, Huang, Xiaojun, Qin, Zhen, Deng, Zhaomin, Luo, Jun, Wang, Baoning, Li, Mingyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988762/ https://www.ncbi.nlm.nih.gov/pubmed/27532886 http://dx.doi.org/10.1371/journal.pone.0160087

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