Cargando…

A Robust and Efficient Production and Purification Procedure of Recombinant Alzheimers Disease Methionine-Modified Amyloid-β Peptides

An improved production and purification method for Alzheimer’s disease related methionine-modified amyloid-β 1–40 and 1–42 peptides is proposed, taking advantage of the formation of inclusion body in Escherichia coli. A Thioflavin-S assay was set-up to evaluate inclusion body formation during growth...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoarau, Marie, Malbert, Yannick, Irague, Romain, Hureau, Christelle, Faller, Peter, Gras, Emmanuel, André, Isabelle, Remaud-Siméon, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988814/
https://www.ncbi.nlm.nih.gov/pubmed/27532547
http://dx.doi.org/10.1371/journal.pone.0161209