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Tempo and mode of genome evolution in a 50,000-generation experiment
Adaptation by natural selection depends on the rates, effects, and interactions of many mutations, making it difficult to determine what proportion of mutations in an evolving lineage are beneficial. We analysed 264 complete genomes from 12 Escherichia coli populations to characterize their dynamics...
Autores principales: | Tenaillon, Olivier, Barrick, Jeffrey E., Ribeck, Noah, Deatherage, Daniel E., Blanchard, Jeffrey L., Dasgupta, Aurko, Wu, Gabriel C., Wielgoss, Sébastien, Cruveiller, Stéphane, Médigue, Claudine, Schneider, Dominique, Lenski, Richard E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988878/ https://www.ncbi.nlm.nih.gov/pubmed/27479321 http://dx.doi.org/10.1038/nature18959 |
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