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The Evolution of Per-cell Organelle Number

Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene products have created an obligate codependence. This...

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Autor principal: Cole, Logan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988970/
https://www.ncbi.nlm.nih.gov/pubmed/27588285
http://dx.doi.org/10.3389/fcell.2016.00085
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author Cole, Logan W.
author_facet Cole, Logan W.
author_sort Cole, Logan W.
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description Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene products have created an obligate codependence. This relationship has played a role in shaping the number of organelles in cells through evolution. Factors such as stochastic evolutionary forces acting on genes involved in organelle biogenesis, organelle–nuclear gene interactions, and physical limitations may, to varying degrees, dictate the selective constraint that per-cell organelle number is under. In particular, coordination between nuclear and organellar gene expression may be important in maintaining gene product stoichiometry, which may have a significant role in constraining the evolution of this trait.
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spelling pubmed-49889702016-09-01 The Evolution of Per-cell Organelle Number Cole, Logan W. Front Cell Dev Biol Cell and Developmental Biology Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene products have created an obligate codependence. This relationship has played a role in shaping the number of organelles in cells through evolution. Factors such as stochastic evolutionary forces acting on genes involved in organelle biogenesis, organelle–nuclear gene interactions, and physical limitations may, to varying degrees, dictate the selective constraint that per-cell organelle number is under. In particular, coordination between nuclear and organellar gene expression may be important in maintaining gene product stoichiometry, which may have a significant role in constraining the evolution of this trait. Frontiers Media S.A. 2016-08-18 /pmc/articles/PMC4988970/ /pubmed/27588285 http://dx.doi.org/10.3389/fcell.2016.00085 Text en Copyright © 2016 Cole. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Cole, Logan W.
The Evolution of Per-cell Organelle Number
title The Evolution of Per-cell Organelle Number
title_full The Evolution of Per-cell Organelle Number
title_fullStr The Evolution of Per-cell Organelle Number
title_full_unstemmed The Evolution of Per-cell Organelle Number
title_short The Evolution of Per-cell Organelle Number
title_sort evolution of per-cell organelle number
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988970/
https://www.ncbi.nlm.nih.gov/pubmed/27588285
http://dx.doi.org/10.3389/fcell.2016.00085
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