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microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes
MicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs. The genomic locations of animal miRNAs are significantly clustered in discrete loci. We found duplication and de novo formation were important mechanisms to create miRNA clusters and the clustered miRNAs tend to be evolutionarily co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989102/ https://www.ncbi.nlm.nih.gov/pubmed/27189568 http://dx.doi.org/10.1093/molbev/msw089 |