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Combinatorial Gene Regulatory Functions Underlie Ultraconserved Elements in Drosophila
Ultraconserved elements (UCEs) are discrete genomic elements conserved across large evolutionary distances. Although UCEs have been linked to multiple facets of mammalian gene regulation their extreme evolutionary conservation remains largely unexplained. Here, we apply a computational approach to i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989106/ https://www.ncbi.nlm.nih.gov/pubmed/27247329 http://dx.doi.org/10.1093/molbev/msw101 |