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Combinatorial Gene Regulatory Functions Underlie Ultraconserved Elements in Drosophila

Ultraconserved elements (UCEs) are discrete genomic elements conserved across large evolutionary distances. Although UCEs have been linked to multiple facets of mammalian gene regulation their extreme evolutionary conservation remains largely unexplained. Here, we apply a computational approach to i...

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Detalles Bibliográficos
Autores principales: Warnefors, Maria, Hartmann, Britta, Thomsen, Stefan, Alonso, Claudio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989106/
https://www.ncbi.nlm.nih.gov/pubmed/27247329
http://dx.doi.org/10.1093/molbev/msw101