Simple steatosis sensitizes cholestatic rats to liver injury and dysregulates bile salt synthesis and transport

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. It is uncertain if simple steatosis, the initial and prevailing form of NAFLD, sensitizes the liver to cholestasis. Here, we compared the effects of obstructive cholestasis in rats with a normal liver versus rats wit...

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Detalles Bibliográficos
Autores principales: Lionarons, Daniël A., Heger, Michal, van Golen, Rowan F., Alles, Lindy K., van der Mark, Vincent A., Kloek, Jaap J., de Waart, Dirk R., Marsman, Hendrik A., Rusch, Henny, Verheij, Joanne, Beuers, Ulrich, Paulusma, Coen C., van Gulik, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989137/
https://www.ncbi.nlm.nih.gov/pubmed/27535001
http://dx.doi.org/10.1038/srep31829

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