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A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects
For region-based sequencing data, power to detect genetic associations can be improved through analysis of multiple related phenotypes. With this motivation, we propose a novel test to detect association simultaneously between a set of rare variants, such as those obtained by sequencing in a small g...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989219/ https://www.ncbi.nlm.nih.gov/pubmed/26860061 http://dx.doi.org/10.1038/ejhg.2016.8 |