Cargando…
A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation
Carbon nanotube (CNT) nanoporous membranes based on pre-aligned CNTs have superior nano-transportation properties in biological science. Herein, we report a smart temperature- and temperature-magnetic-responsive CNT nanoporous membrane (CNM) by grafting thermal-sensitive poly(N-isopropylacrylamide)...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989442/ https://www.ncbi.nlm.nih.gov/pubmed/27535103 http://dx.doi.org/10.1038/srep32130 |
_version_ | 1782448572277456896 |
---|---|
author | Cong, Hailin Xu, Xiaodan Yu, Bing Yang, Zhaohui Zhang, Xiaoyan |
author_facet | Cong, Hailin Xu, Xiaodan Yu, Bing Yang, Zhaohui Zhang, Xiaoyan |
author_sort | Cong, Hailin |
collection | PubMed |
description | Carbon nanotube (CNT) nanoporous membranes based on pre-aligned CNTs have superior nano-transportation properties in biological science. Herein, we report a smart temperature- and temperature-magnetic-responsive CNT nanoporous membrane (CNM) by grafting thermal-sensitive poly(N-isopropylacrylamide) (PNIPAM) and Fe(3)O(4) nanoparticles (Fe(3)O(4)-NPs) on the open ends of pre-aligned CNTs with a diameter around 15 nm via surface-initiated atom transfer radical polymerization (SI-ATRP) method. The inner cavity of the modified CNTs in the membrane is designed to be the only path for ion and protein transportation, and its effective diameter with a variation from ~5.7 nm to ~12.4 nm can be reversible tuned by temperature and magnetic field. The PNIPAM modified CNM (PNIPAM-CNM) and PNIPAM magnetic nanoparticles modified CNM (PNIPAM-MAG-CNM) exhibit excellent temperature- or temperature-magnetic-responsive gating property to separate proteins of different sizes. The PNIPAM-CNMs and PNIPAM-MAG-CNMs have potential applications in making artificial cells, biosensors, bioseparation and purification filters. |
format | Online Article Text |
id | pubmed-4989442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-49894422016-08-30 A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation Cong, Hailin Xu, Xiaodan Yu, Bing Yang, Zhaohui Zhang, Xiaoyan Sci Rep Article Carbon nanotube (CNT) nanoporous membranes based on pre-aligned CNTs have superior nano-transportation properties in biological science. Herein, we report a smart temperature- and temperature-magnetic-responsive CNT nanoporous membrane (CNM) by grafting thermal-sensitive poly(N-isopropylacrylamide) (PNIPAM) and Fe(3)O(4) nanoparticles (Fe(3)O(4)-NPs) on the open ends of pre-aligned CNTs with a diameter around 15 nm via surface-initiated atom transfer radical polymerization (SI-ATRP) method. The inner cavity of the modified CNTs in the membrane is designed to be the only path for ion and protein transportation, and its effective diameter with a variation from ~5.7 nm to ~12.4 nm can be reversible tuned by temperature and magnetic field. The PNIPAM modified CNM (PNIPAM-CNM) and PNIPAM magnetic nanoparticles modified CNM (PNIPAM-MAG-CNM) exhibit excellent temperature- or temperature-magnetic-responsive gating property to separate proteins of different sizes. The PNIPAM-CNMs and PNIPAM-MAG-CNMs have potential applications in making artificial cells, biosensors, bioseparation and purification filters. Nature Publishing Group 2016-08-18 /pmc/articles/PMC4989442/ /pubmed/27535103 http://dx.doi.org/10.1038/srep32130 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Cong, Hailin Xu, Xiaodan Yu, Bing Yang, Zhaohui Zhang, Xiaoyan A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title | A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title_full | A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title_fullStr | A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title_full_unstemmed | A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title_short | A smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
title_sort | smart temperature and magnetic-responsive gating carbon nanotube membrane for ion and protein transportation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989442/ https://www.ncbi.nlm.nih.gov/pubmed/27535103 http://dx.doi.org/10.1038/srep32130 |
work_keys_str_mv | AT conghailin asmarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT xuxiaodan asmarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT yubing asmarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT yangzhaohui asmarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT zhangxiaoyan asmarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT conghailin smarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT xuxiaodan smarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT yubing smarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT yangzhaohui smarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation AT zhangxiaoyan smarttemperatureandmagneticresponsivegatingcarbonnanotubemembraneforionandproteintransportation |