IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study

BACKGROUND: The CD8(+) T cell immune response fights acute infections by intracellular pathogens and, by generating an immune memory, enables immune responses against secondary infections. Activation of the CD8(+) T cell immune response involves a succession of molecular events leading to modificati...

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Detalles Bibliográficos
Autores principales: Gao, Xuefeng, Arpin, Christophe, Marvel, Jacqueline, Prokopiou, Sotiris A., Gandrillon, Olivier, Crauste, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989479/
https://www.ncbi.nlm.nih.gov/pubmed/27535120
http://dx.doi.org/10.1186/s12918-016-0323-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989479/
https://www.ncbi.nlm.nih.gov/pubmed/27535120
http://dx.doi.org/10.1186/s12918-016-0323-y

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