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Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
BACKGROUND: Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification. However, it is not fully understood how individual stem cells exit the pluripotent state and transition towards their respective...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989499/ https://www.ncbi.nlm.nih.gov/pubmed/27534536 http://dx.doi.org/10.1186/s13059-016-1033-x |