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De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohist...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989565/ https://www.ncbi.nlm.nih.gov/pubmed/27601827 http://dx.doi.org/10.4103/0973-029X.185911 |
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author | Sengupta, Moumita Das, Indranil Chatterjee, Uttara Majumdar, Boby |
author_facet | Sengupta, Moumita Das, Indranil Chatterjee, Uttara Majumdar, Boby |
author_sort | Sengupta, Moumita |
collection | PubMed |
description | Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain. |
format | Online Article Text |
id | pubmed-4989565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49895652016-09-06 De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence Sengupta, Moumita Das, Indranil Chatterjee, Uttara Majumdar, Boby J Oral Maxillofac Pathol Case Report Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4989565/ /pubmed/27601827 http://dx.doi.org/10.4103/0973-029X.185911 Text en Copyright: © 2016 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Sengupta, Moumita Das, Indranil Chatterjee, Uttara Majumdar, Boby De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title | De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title_full | De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title_fullStr | De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title_full_unstemmed | De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title_short | De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence |
title_sort | de novo myeloid sarcoma involving mandible in a child: report of a rare occurrence |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989565/ https://www.ncbi.nlm.nih.gov/pubmed/27601827 http://dx.doi.org/10.4103/0973-029X.185911 |
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