Cargando…

De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence

Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohist...

Descripción completa

Detalles Bibliográficos
Autores principales: Sengupta, Moumita, Das, Indranil, Chatterjee, Uttara, Majumdar, Boby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989565/
https://www.ncbi.nlm.nih.gov/pubmed/27601827
http://dx.doi.org/10.4103/0973-029X.185911
_version_ 1782448598175186944
author Sengupta, Moumita
Das, Indranil
Chatterjee, Uttara
Majumdar, Boby
author_facet Sengupta, Moumita
Das, Indranil
Chatterjee, Uttara
Majumdar, Boby
author_sort Sengupta, Moumita
collection PubMed
description Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain.
format Online
Article
Text
id pubmed-4989565
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-49895652016-09-06 De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence Sengupta, Moumita Das, Indranil Chatterjee, Uttara Majumdar, Boby J Oral Maxillofac Pathol Case Report Myeloid sarcoma (MS) is a rare malignant disease defined as extramedullary infiltration of immature myeloid cells. We reporte a 2-year-old male of isolated MS who presented with swelling over the left side of the body of the mandible. Proper histological examination and adequate panels of immunohistochemical stain led to the accurate diagnosis. Early intervention with systemic chemotherapy regimens based on cytarabine is the treatment of choice. The role of chromosomal aberrations and genetic abnormality related to prognosis remain uncertain. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4989565/ /pubmed/27601827 http://dx.doi.org/10.4103/0973-029X.185911 Text en Copyright: © 2016 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sengupta, Moumita
Das, Indranil
Chatterjee, Uttara
Majumdar, Boby
De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title_full De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title_fullStr De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title_full_unstemmed De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title_short De novo myeloid sarcoma involving mandible in a child: Report of a rare occurrence
title_sort de novo myeloid sarcoma involving mandible in a child: report of a rare occurrence
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989565/
https://www.ncbi.nlm.nih.gov/pubmed/27601827
http://dx.doi.org/10.4103/0973-029X.185911
work_keys_str_mv AT senguptamoumita denovomyeloidsarcomainvolvingmandibleinachildreportofarareoccurrence
AT dasindranil denovomyeloidsarcomainvolvingmandibleinachildreportofarareoccurrence
AT chatterjeeuttara denovomyeloidsarcomainvolvingmandibleinachildreportofarareoccurrence
AT majumdarboby denovomyeloidsarcomainvolvingmandibleinachildreportofarareoccurrence