Frequency of Mi(a) antigen: A pilot study among blood donors

The Miltenberger (Mi) classes represent a group of phenotypes for red cells that carry low frequency antigens associated with the MNSs blood group system. This pilot study was aimed at determining the Mi(a) antigen positivity in the blood donor population in a tertiary care hospital in New Delhi, In...

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Detalles Bibliográficos
Autores principales: Makroo, Raj Nath, Bhatia, Aakanksha, Chowdhry, Mohit, Rosamma, N.L., Karna, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989837/
https://www.ncbi.nlm.nih.gov/pubmed/27488007
http://dx.doi.org/10.4103/0971-5916.187112
Descripción
Sumario:The Miltenberger (Mi) classes represent a group of phenotypes for red cells that carry low frequency antigens associated with the MNSs blood group system. This pilot study was aimed at determining the Mi(a) antigen positivity in the blood donor population in a tertiary care hospital in New Delhi, India. The study was performed between June to August 2014 on eligible blood donors willing to participate. Antigen typing was performed using monoclonal anti-Mia antiserum by tube technique. Only one of the 1000 blood donors (0.1%) tested was found to be Mi(a) antigen positive. The Mi(a) antigen can, therefore, be considered as being rare in the Indian blood donor population.

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