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Evolution in spatially mixed host environments increases divergence for evolved fitness and intrapopulation genetic diversity in RNA viruses
Virus populations may be challenged to evolve in spatially heterogeneous environments, such as mixtures of host cells that pose differing selection pressures. Spatial heterogeneity may select for evolved polymorphisms, where multiple virus subpopulations coexist by specializing on a narrow subset of...
Autores principales: | Morley, Valerie J., Sistrom, Mark, Usme-Ciro, Jose A., Remold, Susanna K., Turner, Paul E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989875/ https://www.ncbi.nlm.nih.gov/pubmed/27774292 http://dx.doi.org/10.1093/ve/vev022 |
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