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Inferring Crohn’s disease association from exome sequences by integrating biological knowledge
BACKGROUND: Exome sequencing has been emerged as a primary method to identify detailed sequence variants associated with complex diseases including Crohn’s disease in the protein-coding regions of human genome. However, constructing an interpretable model for exome sequencing data is challenging bec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989895/ https://www.ncbi.nlm.nih.gov/pubmed/27535358 http://dx.doi.org/10.1186/s12920-016-0189-2 |