The role of the Mre11–Rad50–Nbs1 complex in double-strand break repair—facts and myths

Homologous recombination (HR) initiates double-strand break (DSB) repair by digesting 5′-termini at DSBs, the biochemical reaction called DSB resection, during which DSBs are processed by nucleases to generate 3′ single-strand DNA. Rad51 recombinase polymerizes along resected DNA, and the resulting...

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Detalles Bibliográficos
Autores principales: Takeda, Shunichi, Hoa, Nguyen Ngoc, Sasanuma, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Supplement - ICRR highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990115/
https://www.ncbi.nlm.nih.gov/pubmed/27311583
http://dx.doi.org/10.1093/jrr/rrw034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990115/
https://www.ncbi.nlm.nih.gov/pubmed/27311583
http://dx.doi.org/10.1093/jrr/rrw034

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