Blockade of Inhibitors of Apoptosis Proteins in Combination with Conventional Chemotherapy Leads to Synergistic Antitumor Activity in Medulloblastoma and Cancer Stem-Like Cells

BACKGROUND: Medulloblastoma (MB) is the most common pediatric primary malignant brain tumor. Approximately one-third of MB patients succumb to treatment failure and some survivors suffer detrimental side effects. Hence, the purpose of this study is to explore new therapeutic regimens to overcome che...

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Detalles Bibliográficos
Autores principales: Chen, Shu-Mei, Li, Ying-Ying, Tu, Chiao-Hui, Salazar, Nicole, Tseng, Yuan-Yun, Huang, Shiang-Fu, Hsieh, Ling-Ling, Lui, Tai-Ngar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990200/
https://www.ncbi.nlm.nih.gov/pubmed/27537345
http://dx.doi.org/10.1371/journal.pone.0161299

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