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Mitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate Dehydrogenase
Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP(+)) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochondria thanks to their high affinity to accumulate...
Autores principales: | Elkalaf, Moustafa, Tůma, Petr, Weiszenstein, Martin, Polák, Jan, Trnka, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990249/ https://www.ncbi.nlm.nih.gov/pubmed/27537184 http://dx.doi.org/10.1371/journal.pone.0161413 |
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