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A Robust Protocol for Using Multiplexed Droplet Digital PCR to Quantify Somatic Copy Number Alterations in Clinical Tissue Specimens

The ability of droplet digital PCR (ddPCR) to accurately determine the concentrations of amplifiable targets makes it a promising platform for measuring copy number alterations (CNAs) in genomic biomarkers. However, its application to clinical samples, particularly formalin-fixed paraffin-embedded s...

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Detalles Bibliográficos
Autores principales:	Hughesman, Curtis B., Lu, X. J. David, Liu, Kelly Y. P., Zhu, Yuqi, Poh, Catherine F., Haynes, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990255/ https://www.ncbi.nlm.nih.gov/pubmed/27537682 http://dx.doi.org/10.1371/journal.pone.0161274

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