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A Tmprss2-CreER(T2) Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon

Fusion between TMPRSS2 and ERG, placing ERG under the control of the TMPRSS2 promoter, is the most frequent genetic alteration in prostate cancer, present in 40–50% of cases. The fusion event is an early, if not initiating, event in prostate cancer, implicating the TMPRSS2-positive prostate epitheli...

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Detalles Bibliográficos
Autores principales:	Gao, Dong, Zhan, Yu, Di, Wei, Moore, Amanda R., Sher, Jessica J., Guan, Youxin, Wang, Shangqian, Zhang, Zeda, Murphy, Devan A., Sawyers, Charles L., Chi, Ping, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990297/ https://www.ncbi.nlm.nih.gov/pubmed/27536883 http://dx.doi.org/10.1371/journal.pone.0161084

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