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Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ

Cyclooxygenase (COX)-2 selective inhibitors suppress non-alcoholic fatty liver disease (NAFLD); however, the precise mechanism of action remains unknown. The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)-induce...

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Detalles Bibliográficos
Autores principales:	Tsujimoto, Shunsuke, Kishina, Manabu, Koda, Masahiko, Yamamoto, Yasutaka, Tanaka, Kohei, Harada, Yusuke, Yoshida, Akio, Hisatome, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990319/ https://www.ncbi.nlm.nih.gov/pubmed/27431935 http://dx.doi.org/10.3892/ijmm.2016.2674

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