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Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding

[Image: see text] The four-way (Holliday) DNA junction of homologous recombination is processed by the symmetrical cleavage of two strands by a nuclease. These junction-resolving enzymes bind to four-way junctions in dimeric form, distorting the structure of the junction in the process. Crystal stru...

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Detalles Bibliográficos
Autores principales: Freeman, Alasdair D. J., Stevens, Michael, Declais, Anne-Cecile, Leahy, Adam, Mackay, Katherine, El Mkami, Hassane, Lilley, David M. J., Norman, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990344/
https://www.ncbi.nlm.nih.gov/pubmed/27387136
http://dx.doi.org/10.1021/acs.biochem.6b00242