Cargando…
Dexamethasone-(C(21)-phosphoramide)-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549)
PURPOSE: Corticosteroids are effective in the management of a variety of disease states, such as several forms of neoplasia (leukemia and lymphoma), autoimmune conditions, and severe inflammatory responses. Molecular strategies that selectively “target” delivery of corticosteroids minimize or preven...
Autores principales: | Coyne, Cody P, Narayanan, Lakshmi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990379/ https://www.ncbi.nlm.nih.gov/pubmed/27574398 http://dx.doi.org/10.2147/DDDT.S102075 |
Ejemplares similares
-
Gemcitabine‐(5′‐phosphoramidate)‐[anti‐IGF‐1R]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency in populations of pulmonary adenocarcinoma (A549)
por: Coyne, Cody P., et al.
Publicado: (2016) -
Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2′‐Deoxypseudoisocytidine
por: Serpi, Michaela, et al.
Publicado: (2017) -
DNA polymerase activity on synthetic N3′→P5′ phosphoramidate DNA templates
por: Lelyveld, Victor S, et al.
Publicado: (2019) -
New Amides and Phosphoramidates Containing Selenium: Studies on Their Cytotoxicity and Antioxidant Activities in Breast Cancer
por: Etxebeste-Mitxeltorena, Mikel, et al.
Publicado: (2021) -
Phosphoramidates and phosphonamidates (ProTides) with antiviral activity
por: Slusarczyk, Magdalena, et al.
Publicado: (2018)