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Tf-PEG-PLL-PLGA nanoparticles enhanced chemosensitivity for hypoxia-responsive tumor cells

Hypoxia is an inseparable component of the solid tumor as well as the bone marrow microenvironment. In this study, we investigated the effect of the novel polyethylene glycol (PEG)-poly L-lysine (PLL)-poly lactic-co-glycolic acid (PLGA) based nanoparticles (NPs) modified by transferrin (Tf) loaded w...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Zhang, Haijun, Wu, Xue, Guo, Liting, Wang, Fei, Xia, Guohua, Chen, Baoan, Yin, HaiXiang, Wang, Yonglu, Li, Xueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990384/
https://www.ncbi.nlm.nih.gov/pubmed/27574446
http://dx.doi.org/10.2147/OTT.S108169