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Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

Eukaryotic translation initiation involves two conserved DEAD-box RNA helicases, eIF4A and Ded1p. Here we show that S. cerevisiae eIF4A and Ded1p directly interact with each other and simultaneously with the scaffolding protein eIF4G. We delineate a comprehensive thermodynamic framework for the inte...

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Detalles Bibliográficos
Autores principales:	Gao, Zhaofeng, Putnam, Andrea A, Bowers, Heath A, Guenther, Ulf-Peter, Ye, Xuan, Kindsfather, Audrey, Hilliker, Angela K, Jankowsky, Eckhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990422/ https://www.ncbi.nlm.nih.gov/pubmed/27494274 http://dx.doi.org/10.7554/eLife.16408

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