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Predicted Molecular Effects of Sequence Variants Link to System Level of Disease
Developments in experimental and computational biology are advancing our understanding of how protein sequence variation impacts molecular protein function. However, the leap from the micro level of molecular function to the macro level of the whole organism, e.g. disease, remains barred. Here, we p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990455/ https://www.ncbi.nlm.nih.gov/pubmed/27536940 http://dx.doi.org/10.1371/journal.pcbi.1005047 |