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Punctuated chromatin states regulate Plasmodium falciparum antigenic variation at the intron and 2 kb upstream regions
BACKGROUND: Understanding the regulation mechanism of var gene expression is crucial for explaining antigenic variation in Plasmodium falciparum. Recent work observed that while all var genes produce transcripts, only a few var genes exhibit high expression levels. However, the global regulation of...
Autores principales: | Wang, Chengqi, Adapa, Swamy R., Gibbons, Justin, Sutton, Stephen, Jiang, Rays H. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990864/ https://www.ncbi.nlm.nih.gov/pubmed/27538502 http://dx.doi.org/10.1186/s12864-016-3005-7 |
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