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Malaria in urban, semi-urban and rural areas of southern of Gabon: comparison of the Pfmdr 1 and Pfcrt genotypes from symptomatic children

BACKGROUND: Artesunate-amodiaquine (AS-AQ) and artemether-lumefantrine (AL) are first- and second-line treatments for uncomplicated Plasmodium falciparum malaria in Gabon. AL remains highly efficacious, but its widespread use has led to molecular selection of the NFD haplotype on Pfmdr1 and K76 in P...

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Detalles Bibliográficos
Autores principales: Maghendji-Nzondo, Sydney, Kouna, Lady-Charlène, Mourembou, Gaël, Boundenga, Larson, Imboumy-Limoukou, Romeo-Karl, Matsiegui, Pierre-Blaise, Manego-Zoleko, Rella, Mbatchi, Bertrand, Raoult, Didier, Toure-Ndouo, Fousseyni, Lekana-Douki, Jean Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990874/
https://www.ncbi.nlm.nih.gov/pubmed/27538948
http://dx.doi.org/10.1186/s12936-016-1469-1