The antinociception of oxytocin on colonic hypersensitivity in rats was mediated by inhibition of mast cell degranulation via Ca(2+)-NOS pathway

This study was conducted to investigate the effects of oxytocin (OT) on visceral hypersensitivity/pain and mast cell degranulation and the underlying mechanisms. We found that oxytocin receptor (OTR) was expressed in colonic mast cells in humans and rats, as well as in human mast cell line-1 (HMC-1)...

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Detalles Bibliográficos
Autores principales: Gong, Liping, Li, Jing, Tang, Yan, Han, Ting, Wei, Chuanfei, Yu, Xiao, Li, Jingxin, Wang, Rong, Ma, Xuelian, Liu, Kejing, Geng, Lingyun, Liu, Shaozhuang, Yan, Bing, Liu, Chuanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990927/
https://www.ncbi.nlm.nih.gov/pubmed/27538454
http://dx.doi.org/10.1038/srep31452

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