A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium

PURPOSE: Noncoding microRNAs (miRNAs) have been implicated in the pathogenesis of glaucoma. We aimed to identify common variants in miRNA coding genes (MIR) associated with primary open-angle glaucoma (POAG). METHODS: Using the NEIGHBORHOOD data set (3853 cases/33,480 controls with European ancestry...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yutao, Bailey, Jessica Cooke, Helwa, Inas, Dismuke, W. Michael, Cai, Jingwen, Drewry, Michelle, Brilliant, Murray H., Budenz, Donald L., Christen, William G., Chasman, Daniel I., Fingert, John H., Gaasterland, Douglas, Gaasterland, Terry, Gordon, Mae O., Igo, Robert P., Kang, Jae H., Kass, Michael A., Kraft, Peter, Lee, Richard K., Lichter, Paul, Moroi, Sayoko E., Realini, Anthony, Richards, Julia E., Ritch, Robert, Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Song, Yeunjoo E., Vollrath, Douglas, Weinreb, Robert, Medeiros, Felipe, Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Pericak-Vance, Margaret A., Gonzalez, Pedro, Stamer, W. Daniel, Kuchtey, John, Kuchtey, Rachel W., Allingham, R. Rand, Hauser, Michael A., Pasquale, Louis R., Haines, Jonathan L., Wiggs, Janey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991020/
https://www.ncbi.nlm.nih.gov/pubmed/27537254
http://dx.doi.org/10.1167/iovs.16-19688

Ejemplares similares

Ejemplares similares