Cargando…

Improved dissolution and anti-inflammatory activity of ibuprofen-polyethylene glycol 8000 solid dispersion systems

BACKGROUND: The purpose of this study was to develop ibuprofen (IB)-polyethylene glycol (PEG) 8000 solid dispersions (SDs) and investigate them for in vitro dissolution and in vivo anti-inflammatory activity. MATERIALS AND METHODS: IB-PEG 8000 SDs were prepared by fusion method using varying combina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ofokansi, Kenneth C., Kenechukwu, Franklin C., Ezugwu, Richard O., Attama, Anthony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2016
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991122/ https://www.ncbi.nlm.nih.gov/pubmed/27606257 http://dx.doi.org/10.4103/2230-973X.187344

Ejemplares similares

Formulation Development and Evaluation of Drug Release Kinetics from Colon-Targeted Ibuprofen Tablets Based on Eudragit RL 100-Chitosan Interpolyelectrolyte Complexes
por: Ofokansi, Kenneth Chibuzor, et al.
Publicado: (2013)

Development of a binary carrier system consisting polyethylene glycol 4000 - ethyl cellulose for ibuprofen solid dispersion
por: Alagdar, Gada Sulaiman A., et al.
Publicado: (2017)

Erratum: Development of a binary carrier system consisting polyethylene glycol 4000 - ethyl cellulose for ibuprofen solid dispersion
Publicado: (2017)

Synthesis of Stable Cholesteryl–Polyethylene Glycol–Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths
por: Cristóbal-Lecina, Edgar, et al.
Publicado: (2020)

Development and Evaluation of Novel Self-Nanoemulsifying Drug Delivery Systems Based on a Homolipid from Capra hircus and Its Admixtures with Melon Oil for the Delivery of Indomethacin
por: Obitte, Nicholas C., et al.
Publicado: (2014)

Investigation of novel solid lipid microparticles based on homolipids from Bos indicus for the delivery of gentamicin
por: Kenechukwu, Franklin C., et al.
Publicado: (2016)

Surface-modified mucoadhesive microparticles as a controlled release system for oral delivery of insulin
por: Mumuni, Momoh A., et al.
Publicado: (2019)

Intrusion of polyethylene glycol into solid-state nanopores
por: Sun, Yueting, et al.
Publicado: (2018)

Mechanistic insights into acyclovir-polyethylene glycol 20000 binary dispersions
por: Venkateskumar, Krishnamoorthy, et al.
Publicado: (2016)

Altitude 8000
por: Murail, Tristan
Publicado: (1975)

Enhancement of dissolution of Telmisartan through use of solid dispersion technique - surface solid dispersion
por: Patel, Bhumika, et al.
Publicado: (2012)

Contribution of Crystal Lattice Energy on the Dissolution Behavior of Eutectic Solid Dispersions
por: Chaturvedi, Kaushalendra, et al.
Publicado: (2020)

In vitro Dissolution Studies on Solid Dispersions of Mefenamic Acid
por: Rao, K. R. S. Sambasiva, et al.
Publicado: (2011)

Dissolution enhancement of efavirenz by solid dispersion and PEGylation techniques
por: Madhavi, B. Bindu, et al.
Publicado: (2011)

In vitro dissolution study of atorvastatin binary solid dispersion
por: Jahan, Rahat, et al.
Publicado: (2013)

Thermodynamics of dissolution and infrared-spectroscopy of solid dispersions of phenacetin
por: Gerasimov, Alexander V., et al.
Publicado: (2016)

Mechanism and Improved Dissolution of Glycyrrhetinic Acid Solid Dispersion by Alkalizers
por: Dong, Luning, et al.
Publicado: (2020)

Anti-Inflammatory and Gastroprotective Properties of Aspirin - Entrapped Solid Lipid Microparticles
por: Chime, Salome A., et al.
Publicado: (2020)

Characterization, in Vivo and in Vitro Evaluation of Solid Dispersion of Curcumin Containing d-α-Tocopheryl Polyethylene Glycol 1000 Succinate and Mannitol
por: Song, Im-Sook, et al.
Publicado: (2016)

Development, in vitro and in vivo evaluations of novel lipid drug delivery system of Newbouldia laevis (P. Beauv.)
por: Umeyor, Chukwuebuka, et al.
Publicado: (2016)

Synthesis and Characterization of Polyethylene Glycol-Grafted Photoreactive Polyethylene Glycols for Antibiofouling Applications
por: Othman, Mahmoud H., et al.
Publicado: (2022)

FORMULATION OF FUROSEMIDE SOLID DISPERSION WITH MICRO CRYSTALLINE CELLULOSE FOR ACHIEVE RAPID DISSOLUTION
por: Patel, Rajanikant C., et al.
Publicado: (2010)

Improvement of Solubility and Dissolution Properties of Clotrimazole by Solid Dispersions and Inclusion Complexes
por: Balata, Gehan, et al.
Publicado: (2011)

The Effect of PEG Molecular Weights on Dissolution Behavior of Simvastatin in Solid Dispersions
por: Bolourchian, Noushin, et al.
Publicado: (2013)

Formulation Development and Dissolution Rate Enhancement of Efavirenz by Solid Dispersion Systems
por: Koh, P. T., et al.
Publicado: (2013)

Bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400, and polyethylene glycol 1000 against selected microorganisms
por: Nalawade, Triveni Mohan, et al.
Publicado: (2015)

The blood DNA virome in 8,000 humans
por: Moustafa, Ahmed, et al.
Publicado: (2017)

Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability
por: Han, Fei, et al.
Publicado: (2019)

Physical Stability and Dissolution of Lumefantrine Amorphous Solid Dispersions Produced by Spray Anti-Solvent Precipitation
por: Bhujbal, Sonal V., et al.
Publicado: (2021)

Solubility and Dissolution Enhancement of Etoricoxib by Solid Dispersion Technique Using Sugar Carriers
por: Das, Abhisekh, et al.
Publicado: (2011)

Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
por: Zhang, Qi, et al.
Publicado: (2017)

Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution Evaluation
por: Adibkia, Khosro, et al.
Publicado: (2019)

Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions
por: Monschke, Marius, et al.
Publicado: (2020)

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution
por: Yeo, Sooho, et al.
Publicado: (2020)

Investigating the molecular dissolution process of binary solid dispersions by molecular dynamics simulations
por: Chan, TengIan, et al.
Publicado: (2018)

Long-term stability of clopidogrel solid dispersions—Importance of in vitro dissolution test
por: Osmanović Omerdić, Ehlimana, et al.
Publicado: (2022)

Nanoseeded Desupersaturation and Dissolution Tests for Elucidating Supersaturation Maintenance in Amorphous Solid Dispersions
por: Guner, Gulenay, et al.
Publicado: (2023)

Effect of Molecular Weight on the Dissolution Profiles of PEG Solid Dispersions Containing Ketoprofen
por: Le Khanh, Ha Pham, et al.
Publicado: (2023)

Investigating the Dissolution Performance of Amorphous Solid Dispersions Using Magnetic Resonance Imaging and Proton NMR
por: Tres, Francesco, et al.
Publicado: (2015)

Polyethylene Glycol 3350 With Electrolytes Versus Polyethylene Glycol 4000 for Constipation: A Randomized, Controlled Trial
por: Bekkali, Noor L.H., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qcro8o7vlt1l6t44tt67i1koi7